Untreated Childhood Supratentorial Primitive Neuroectodermal Tumors and Pineoblastoma

Untreated childhood supratentorial primitive neuroectodermal tumors and pineoblastoma are tumors for which no treatment has been given. The child may have received drugs or treatment to relieve symptoms caused by the tumor.

Standard treatment of supratentorial neuroectodermal tumors or pineoblastoma in children 3 years of age and older may include the following:

• Surgery.
• Surgery followed by radiation therapy to the whole brain and spinal cord.
• Surgery followed by radiation therapy to the whole brain and spinal cord, and chemotherapy.

Some of the treatments being studied in clinical trials for supratentorial neuroectodermal tumors or pineoblastoma in children 3 years of age and older include the following:

• A clinical trial of chemotherapy given before or after radiation therapy.
• A clinical trial of chemotherapy to delay or reduce the need for radiation therapy.

Standard treatment of supratentorial neuroectodermal tumors or pineoblastoma in children younger than 3 years of age may include the following:

• Surgery.
• Surgery followed by chemotherapy.

One of the treatments being studied in clinical trials for supratentorial neuroectodermal tumors or pineoblastoma in children younger than 3 years of age includes chemotherapy to delay or reduce the need for radiation therapy.

Information about these and other ongoing clinical trials is available from the NCI Cancer.gov Web site.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with untreated childhood supratentorial primitive neuroectodermal tumors and untreated childhood pineoblastoma.

Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumors and Pineoblastoma

Standard treatment of recurrent childhood supratentorial primitive neuroectodermal tumors and pineoblastoma may include the following:

• Surgery.
• Chemotherapy.

New treatments are being studied in clinical trials for recurrent childhood supratentorial primitive neuroectodermal tumors and pineoblastoma. Information about this and other ongoing clinical trials is available from the NCI Cancer.gov Web site.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent childhood supratentorial primitive neuroectodermal tumors and recurrent childhood pineoblastoma.