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Cancer Health Center

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Cancer Prevention Overview (PDQ®): Prevention - Patient Information [NCI] - Interventions That are Known to Lower Cancer Risk

An intervention is a treatment or action taken to prevent or treat disease, or improve health in other ways. Many studies are being done to find ways to keep cancer from starting or recurring (coming back).

Chemoprevention is being studied in patients who have a high risk of developing cancer.

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Note: Separate PDQ summaries on Oral Cancer Prevention and Lip and Oral Cavity Cancer Treatment are also available. Benefits There is inadequate evidence to establish whether screening would result in a decrease in mortality from oral cancer. Magnitude of Effect: No evidence of benefit or harm. Study Design: Evidence obtained from one randomized controlled trial. Internal Validity: Poor. Consistency: Not applicable (N/A). External...

Read the Overview article > >

Chemoprevention is the use of substances to lower the risk of cancer, or keep it from recurring. The substances may be natural or made in the laboratory. Some chemopreventive agents are tested in people who are at high risk for a certain type of cancer. The risk may be because of a precancerous condition, family history, or lifestyle factors.

Some chemoprevention studies have shown good results. For example, selective estrogen receptor modulators (SERMS) such as tamoxifen or raloxifene have been shown to reduce the risk of breast cancer in women at high risk. Finasteride and dutasteride have been shown to reduce the risk of prostate cancer.

See the following PDQ summaries for more information:

New ways to prevent cancer are being studied in clinical trials.

Chemoprevention agents that are being studied in clinical trials include COX-2 inhibitors. They are being studied for the prevention of colorectal and breast cancer. Aspirin is being studied for the prevention of colorectal cancer.

See the following PDQ summaries for more information:

Clinical trials are taking place in many parts of the country. Check NCI's PDQ Cancer Clinical Trials Registry for cancer prevention trials that are now accepting patients.

See the NCI Web site for more information about cancer prevention.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: 8/, 015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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