Treatment Options for Stages I and II
Complete surgical resection of primary tumor followed by chemotherapy.In a randomized trial, seven of eight patients with stage I hepatocellular carcinoma survived disease free after adjuvant cisplatin-based chemotherapy. In a survey of childhood liver tumors treated prior to the consistent use of chemotherapy, only 12 of 33 patients with hepatocellular carcinoma who had complete excision of the tumor survived. This suggests that adjuvant chemotherapy...
Added text about an open-label extension study of 43 patients that found that some patients continued to obtain relief of their cancer-related pain with long-term use of the delta-9-tetrahydrocannabinol:cannabidiol oromucosal spray without increasing their dose of the spray or the dose of their other analgesics (cited Johnson et al. as reference 38).
Added text about a randomized controlled trial of 39 patients with neuropathic pain who were treated with medium-dose, low-dose or placebo vaporized Cannabis that found that vaporized Cannabis produced comparable analgesic effects at both doses compared with placebo; psychoactive effects were minimal and well tolerated (cited Wilsey et al. as reference 42).
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