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Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to this Summary (01 / 23 / 2013)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Postinduction Treatment for Specific ALL Subgroups

Recommended Related to Cancer

Treatment of Undifferentiated Embryonal Sarcoma of the Liver

Treatment Options Undifferentiated embryonal sarcoma of the liver is so rare that only small series have been published regarding treatment. However, use of aggressive chemotherapy regimens seems to have improved the overall survival (OS). The generally accepted approach is to resect the primary tumor mass in the liver when possible. Neoadjuvant chemotherapy can be effective in decreasing an unresectable primary tumor mass, resulting in resectability.[1,2,3,4] The OS of these children appears...

Read the Treatment of Undifferentiated Embryonal Sarcoma of the Liver article > >

Revised text to state that the pilot study showed a 5-year event-free survival rate of 73% for all patients receiving nelarabine and 69% for those patients with a slow early response (cited Dunsmore et al. as reference 10).

Added Ram et al. as reference 32.

Treatment of Recurrent Childhood ALL

Added Leung et al. as reference 54.

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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