Purpose of This Summary
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of adult soft tissue sarcoma. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.
Reviewers and Updates
This summary is reviewed regularly and updated as necessary by the PDQ Adult Treatment...
Added text about a Children's Oncology Group study that evaluated surveillance computed tomography (CT) and detection of relapse in intermediate-stage and advanced-stage Hodgkin lymphoma; the routine use of CT at the intervals used in this study did not improve outcome (cited Voss et al. as reference 31).
Treatment for Newly Diagnosed Children and Adolescents with Hodgkin Lymphoma
Added text to state that involved-nodal radiation therapy (RT) defines the treatment volume using the prechemotherapy positron emission tomography (PET)/CT scan that is obtained with the patient positioned in a similar manner to the position that will be used at the time of RT. This volume is later contoured onto the postchemotherapy-planning CT scan; the final treatment volume only includes the initially involved nodes with a margin, typically 2 cm.
Added text about involved-site RT, the indications for use, and the size of the treatment volumes.
Added text to state that proton therapy is currently being investigated and may further decrease the mean dose to the surrounding normal tissue compared with intensity-modulated RT or 3-dimensional conformal RT, without increasing the volume of normal tissue receiving lower-dose radiation.
Treatment of Primary Refractory/Recurrent Hodgkin Lymphoma in Children and Adolescents
Added Gorde-Grosjean et al. as reference 4.
This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.