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    Childhood Hodgkin Lymphoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Childhood Hodgkin Lymphoma

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    There are three ways that cancer spreads in the body.

    Cancer can spread through tissue, the lymph system, and the blood:

    • Tissue. The cancer spreads from where it began by growing into nearby areas.
    • Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.
    • Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body.

    Stages of childhood Hodgkin lymphoma may include A, B, E, and S.

    Childhood Hodgkin lymphoma may be described as follows:

    • A: The patient does not have B symptoms (fever, weight loss, or night sweats).
    • B: The patient has B symptoms.
    • E: Cancer is found in an organ or tissue that is not part of the lymph system but which may be next to an involved area of the lymph system.
    • S: Cancer is found in the spleen.

    The following stages are used for childhood Hodgkin lymphoma:

    Stage I

    cdr0000648701.jpg
    Stage I childhood Hodgkin lymphoma. Cancer is found in one or more lymph nodes in one lymph node group. In stage IE (not shown), cancer is found outside the lymph nodes in one organ or area.

    Stage I is divided into stage I and stage IE.

    • Stage I: Cancer is found in one of the following places in the lymph system:
      • One or more lymph nodes in one lymph node group.
      • Waldeyer's ring.
      • Thymus.
      • Spleen.
    • Stage IE: Cancer is found outside the lymph system in one organ or area.

    Stage II

    Stage II is divided into stage II and stage IIE.

    • Stage II: Cancer is found in two or more lymph node groups either above or below the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen).
      cdr0000648702.jpg
      Stage II childhood Hodgkin lymphoma. Cancer is found in two or more lymph node groups, and both are either above (a) or below (b) the diaphragm.
    • Stage IIE: Cancer is found in one or more lymph node groups either above or below the diaphragm and outside the lymph nodes in a nearby organ or area.
      cdr0000648703.jpg
      Stage IIE childhood Hodgkin lymphoma. Cancer is found in one or more lymph node groups above or below the diaphragm and outside the lymph nodes in a nearby organ or area (a).
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