Mistletoe is a semiparasitic plant that grows on several types of common trees such as apple, oak, pine, and elm. Mistletoe extract has been used since ancient times to treat many ailments (see Question 1).
Mistletoe is one of the most widely studied complementary and alternative medicine therapies in people with cancer. In certain European countries, preparations made from European mistletoe are among the most prescribed drugs for patients with cancer (see Question 1).
Added text about a European trial of adults with completely resected soft tissue sarcoma who were randomly assigned to observation or adjuvant chemotherapy with ifosfamide and doxorubicin, using a relatively low dose of ifosfamide. Adjuvant chemotherapy was not associated with improved event-free survival or overall survival; when the authors merged their patients with previously published series, they concluded that the results suggested a benefit for adjuvant chemotherapy (cited Woll et al. as reference 30 and level of evidence 1iiA).
Treatment of Newly Diagnosed Childhood Soft Tissue Sarcoma
Added text to state that expression and genomic index prognostic signatures have been studied in synovial sarcoma; more complex genomic profiles, with greater rearrangement of the genome, are more common in adults than in younger patients with synovial sarcoma and are associated with a higher risk for metastasis (cited Lagarde et al. as reference 134).
Added text to state that angiosarcomas or lymphangiosarcomas may arise in a setting of benign vascular anomalies or vascular malformations (cited Al Dhaybi et al. and Rossi et al. as references 150 and 151, respectively).
This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.
In this article
This information is produced and provided by the National
Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National
Institute via the Internet web site at http://
.gov or call 1-800-4-CANCER.
WebMD Public Information from the National Cancer Institute
September 04, 2014
This information is not intended to replace the advice of a doctor.
Healthwise disclaims any liability for the decisions you make based on this