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Childhood Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Childhood Soft Tissue Sarcoma

Newly Diagnosed Childhood Soft Tissue Sarcoma

Fat Tissue Tumors

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Overview

This complementary and alternative medicine (CAM) information summary provides an overview of the use of coenzyme Q10 in cancer therapy. The summary includes a history of coenzyme Q10 research, a review of laboratory studies, and data from investigations involving human subjects. Although several naturally occurring forms of coenzyme Q have been identified, Q10 is the predominant form found in humans and most mammals, and it is the form most studied for therapeutic potential. Thus, it will be the...

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Liposarcoma

Treatment of liposarcoma may include the following:

  • Surgery to completely remove the tumor. If the cancer is not completely removed, a second surgery may be done.
  • Chemotherapy to shrink the tumor, followed by surgery.

Bone and Cartilage Tumors

Extraskeletal chondrosarcoma

Treatment of extraskeletal chondrosarcoma may include the following:

  • Surgery to completely remove the tumor.
  • Surgery to remove as much of the tumor as possible, followed by radiation therapy.
  • Combination chemotherapy may be given after surgery to lessen the chance the tumor will spread to the lungs.

Extraskeletal osteosarcoma

Treatment of extraskeletal osteosarcoma may include the following:

  • Surgery to completely remove the tumor.

In children, it is not clear if chemotherapy improves the tumor's response to treatment.

Fibrous (Connective) Tissue Tumors

Desmoid tumor

Treatment of desmoid tumor may include the following:

  • Surgery to completely remove the tumor when possible. Surgery may be followed by radiation therapy if tumor remains.
  • Radiation therapy, if the tumor cannot be removed by surgery.
  • Watchful waiting.

If surgery to completely remove the tumor is not possible, treatment to shrink the tumor before surgery may include the following:

  • Chemotherapy.
  • Antiestrogen therapy.
  • A nonsteroidal anti-inflammatory drug (NSAID).
  • External radiation therapy.

Fibrosarcoma

Infantile fibrosarcoma

Treatment of infantile fibrosarcoma (also called congenital fibrosarcoma) may include the following:

  • Surgery to remove the tumor when possible.
  • Chemotherapy to shrink the tumor, followed by surgery.

Adult-type fibrosarcoma

Treatment of adult-type fibrosarcoma may include the following:

  • Surgery to completely remove the tumor when possible.

Dermatofibrosarcoma protuberans

Treatment of dermatofibrosarcoma protuberans may include the following:

  • Surgery to completely remove the tumor when possible.
  • Radiation therapy if the tumor is not completely removed.
  • Targeted therapy (imatinib) if the tumor cannot be removed or has come back.

Inflammatory myofibroblastic tumor

Treatment of inflammatory myofibroblastic tumor may include the following:

  • Surgery to completely remove the tumor when possible.

Low-grade fibromyxoid sarcoma

There is no standard treatment for low-grade fibromyxoid sarcoma.

Myxofibrosarcoma, low-grade

Treatment of myxofibrosarcoma, low-grade may include the following:

  • Surgery to completely remove the tumor.

Sclerosing epithelioid fibrosarcoma

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