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Chronic Lymphocytic Leukemia Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

Stage 0 Chronic Lymphocytic Leukemia

Treatment of stage 0 chronic lymphocytic leukemia is usually watchful waiting.

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Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 chronic lymphocytic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage I, Stage II, Stage III, and Stage IV Chronic Lymphocytic Leukemia

Treatment of stage I, stage II, stage III, and stage IV chronic lymphocytic leukemia may include the following:

  • Watchful waiting when there are few or no signs or symptoms.
  • Targeted therapy with a monoclonal antibody or a tyrosine kinase inhibitor.
  • Chemotherapy with 1 or more drugs, with or without steroids or monoclonal antibody therapy.
  • Low-dose external radiation therapy to areas of the body where cancer is found, such as the spleen or lymph nodes.
  • A clinical trial of chemotherapy and biologic therapy with stem cell transplant.
  • A clinical trial of biologic therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I chronic lymphocytic leukemia, stage II chronic lymphocytic leukemia, stage III chronic lymphocytic leukemia and stage IV chronic lymphocytic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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