Radiation therapy may be used to treat endometrial cancer. Radiation may be given internally, through the placement of radioactive substances in the uterus or area of cancer (brachytherapy), or externally, through delivery of radiation from an outside source (external beam X-ray).

Radiation treatment of premenopausal ovaries will cause menopause and infertility. Other side effects of radiation can include:¹⁴

• Bowel obstruction.
• Abdominal cramps.
• Frequent bowel movements or diarrhea.
• Chronic bladder irritation.
• Vaginal scarring (vaginal fibrosis).

Studies called clinical trials are being conducted to find ways to prevent, detect, diagnose, and treat endometrial cancer. Talk with your doctor to see whether clinical trials are available and whether you are a good candidate.