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Extrahepatic Bile Duct Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Extrahepatic Bile Duct Cancer

The term, cholangiocarcinoma, is sometimes used to refer to any primary cancer of the biliary system; however, its use is often restricted to intrahepatic tumors and, therefore, it is not included in this summary. Adenocarcinomas are the most common type of extrahepatic bile duct cancers. The histologic types are listed below:[1,2]

  • Carcinomain situ.
  • Adenocarcinoma, not otherwise specified (NOS).
  • Adenocarcinoma, intestinal type.
  • Mucinous adenocarcinoma.
  • Clear cell adenocarcinoma.
  • Signet-ring cell carcinoma.
  • Adenosquamous carcinoma.
  • Squamous cell carcinoma.
  • Small cell (oat cell) carcinoma.
  • Undifferentiated carcinoma.
    • Spindle and giant cell types.
    • Small cell types.
  • Papillomatosis.
  • Papillary carcinoma, noninvasive.
  • Papillary carcinoma, invasive.
  • Carcinoma, NOS.

Malignant mesenchymal tumors, although rare, include the following:

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  • Embryonal rhabdomyosarcoma.
  • Leiomyosarcoma.
  • Malignant fibrous histiocytoma.

References:

  1. Perihilar bile ducts. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 219-22.
  2. Distal bile duct. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 227-33.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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