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Treatment Options for Retinoblastoma

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    For trilateral retinoblastoma, treatment may include the following:

    • Chemotherapy followed by high-dose chemotherapy and stem cell rescue.

    For retinoblastoma that has spread to other parts of the body, treatment may be the following:

    • High-dose chemotherapy and stem cell rescue.
    • A clinical trial of chemotherapy followed by high-dose chemotherapy with stem cell rescue and/or radiation therapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with extraocular retinoblastoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Recurrent Retinoblastoma

    If the cancer is small and in the eye only, treatment is usually local therapy, which may include the following:

    • Plaque radiotherapy.
    • Cryotherapy.
    • Thermotherapy.

    If the cancer around the eye is large and the eye has been removed, treatment is usually the following:

    • Chemotherapy followed by radiation therapy.

    If the cancer comes back outside of the eye, treatment will depend on many things and may be within a clinical trial, which may be the following:

    • Chemotherapy combined with high-dose chemotherapy and stem cell rescue with radiation therapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent retinoblastoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    WebMD Public Information from the National Cancer Institute

    Last Updated: February 25, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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