Newcastle disease virus (NDV) is a virus that is of interest because it replicates (makes copies of itself) more quickly in human cancer cells than in most normal human cells and because it can kill these host cells (see Question 1).
NDV can be used to directly kill cancer cells, or it can be given as a cancervaccine. Cancer vaccines cause the body's natural immune system to seek out and destroy cancer cells (see Question 4).
The results of clinical trials (research studies with people)...
Table 2, Genes Associated with a High Susceptibility of Colorectal Cancer, was extensively revised.
Major Genetic Syndromes
Added text to state that in patients with Peutz-Jeghers syndrome, the cumulative risks have been estimated to be 32% to 54% for breast cancer and 21% for ovarian cancer.
The Juvenile polyposis syndrome (JPS) subsection was comprehensively reviewed and extensively revised.
The CHEK2 subsection was comprehensively reviewed and extensively revised.
The Hereditary mixed polyposis syndrome subsection was comprehensively reviewed and revised.
The Serrated polyposis syndrome/Hyperplastic polyposis syndrome subsection was comprehensively reviewed and extensively revised.
Revised Table 12, Published Recommendations for Diagnosis and Surveillance of JPS, to include text about an additional study (cited Latchford et al. as reference 448).
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WebMD Public Information from the National Cancer Institute
September 04, 2014
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