Treatment Options by Stage
A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.
Stage I Hypopharyngeal Cancer
General Information for Childhood Extracranial Germ Cell Tumors (GCTs)
The National Cancer Institute (NCI) provides the PDQ pediatric cancer treatment information summaries as a public service to increase the availability of evidence-based cancer information to health professionals, patients, and the public. Fortunately, cancer in children and adolescents is rare, although the overall incidence of childhood cancer has been slowly increasing since 1975.[1] Children and adolescents with cancer should be referred to medical centers that have a multidisciplinary team...
Read the General Information for Childhood Extracranial Germ Cell Tumors (GCTs) article > >
Treatment of stage I hypopharyngeal cancer may include the following:
- Laryngopharyngectomy and neck dissection with or without high-doseradiation therapy to the lymph nodes of the neck.
- Partial laryngopharyngectomy with or without high-dose radiation therapy to the lymph nodes on both sides of the neck.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I hypopharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Stage II Hypopharyngeal Cancer
Treatment of stage II hypopharyngeal cancer may include the following:
- Laryngopharyngectomy and neck dissection. High-doseradiation therapy to the lymph nodes of the neck may be given before or after surgery.
- Partial laryngopharyngectomy. High-dose radiation therapy to the lymph nodes of the neck may be given before or after surgery.
- Chemotherapy given during or after radiation therapy or after surgery.
- A clinical trial of chemotherapy followed by radiation therapy or surgery.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II hypopharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Stage III Hypopharyngeal Cancer
Treatment of stage III hypopharyngeal cancer may include the following:
- Radiation therapy before or after surgery.
- Chemotherapy given during or after radiation therapy or after surgery.
- A clinical trial of chemotherapy followed by surgery and/or radiation therapy.
- A clinical trial of chemotherapy given at the same time as radiation therapy.
- A clinical trial of surgery followed by chemotherapy given at the same time as radiation therapy.
Treatment and follow-up of stage III hypopharyngeal cancer is complex and is ideally overseen by a team of specialists with experience and expertise in treating this type of cancer. If all or part of the hypopharynx is removed, the patient may need plastic surgery and other special help with breathing, eating, and talking.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III hypopharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
WebMD Public Information from the National Cancer Institute

