Skip to content

    Cancer Health Center

    Font Size
    A
    A
    A

    Hypopharyngeal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Hypopharyngeal Cancer

    The staging systems are all clinical staging and are based on the best possible estimate of the extent of disease before treatment. The assessment of the primary tumor is based on inspection and palpation, when possible, and by both indirect mirror examination and direct endoscopy. The tumor must be confirmed histologically, and any other pathologic data obtained from a biopsy may be included. Additional radiographic studies may be included. As an adjunct to clinical examination, computed tomography and/or magnetic resonance imaging are needed for an accurate staging of laryngeal and hypopharyngeal carcinomas because both cross-sectional imaging modalities are known to reliably evaluate deep tumor infiltration.[1,2,3] The appropriate nodal drainage areas are examined by careful palpation. If a patient relapses, complete restaging must be done to select the appropriate additional therapy.

    Definitions of TNM

    The American Joint Committee on Cancer has designated staging by TNM classification to define hypopharyngeal cancer.[4]

    Table 1. Primary Tumor (T)a

    a Reprinted with permission from AJCC: Pharynx. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 41-56.
    b Central compartment soft tissue includes prelaryngeal strap muscles and subcutaneous fat.
    TX Primary tumor cannot be assessed.
    T0 No evidence of primary tumor.
    Tis Carcinomain situ.
    Hypopharynx
    T1 Tumor limited to 1 subsite of hypopharynx and/or ≤2 cm in greatest dimension.
    T2 Tumor invades >1 subsite of hypopharynx or an adjacent site, or measures >2 cm but not >4 cm in greatest dimension without fixation of hemilarynx.
    T3 Tumor >4 cm in greatest dimension or with fixation of hemilarynx or extension to esophagus.
    T4a Moderately advanced local disease.
    Tumor invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, or central compartment soft tissue.b
    T4b Very advanced local disease.
    Tumor invades prevertebral fascia, encases carotid artery, or involves mediastinal structures.
    1 | 2 | 3
    1 | 2 | 3
    Next Article:

    Today on WebMD

    man holding lung xray
    What you need to know.
    stem cells
    How they work for blood cancers.
     
    woman wearing pink ribbon
    Separate fact from fiction.
    Colorectal cancer cells
    Symptoms, screening tests, and more.
     
    Jennifer Goodman Linn self-portrait
    Blog
    what is your cancer risk
    HEALTH CHECK
     
    colorectal cancer treatment advances
    Video
    breast cancer overview slideshow
    SLIDESHOW
     
    prostate cancer overview
    SLIDESHOW
    lung cancer overview slideshow
    SLIDESHOW
     
    ovarian cancer overview slideshow
    SLIDESHOW
    Actor Michael Douglas
    Article