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Laryngeal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

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Stage III Laryngeal Cancer

Treatment of stage III laryngeal cancer depends on where cancer is found in the larynx.

If cancer is in the supraglottis or glottis, treatment may include the following:

  • Surgery with or without radiation therapy.
  • Radiation therapy with or without surgery.
  • A clinical trial of radiation therapy.
  • A clinical trial of chemotherapy combined with radiation therapy, with or without laryngectomy.
  • A clinical trial of radiosensitizers.
  • A clinical trial of chemoprevention.

If cancer is in the subglottis, treatment may include the following:

  • Laryngectomy plus total thyroidectomy and removal of lymph nodes in the throat, usually followed by radiation therapy.
  • Radiation therapy with or without surgery.
  • A clinical trial of radiation therapy.
  • A clinical trial of chemotherapy.
  • A clinical trial of radiosensitizers.
  • A clinical trial of chemoprevention.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III laryngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage IV Laryngeal Cancer

Treatment of stage IV laryngeal cancer depends on where cancer is found in the larynx.

If cancer is in the supraglottis or glottis, treatment may include the following:

  • Total laryngectomy with radiation therapy.
  • Radiation therapy with or without surgery.
  • A clinical trial of radiation therapy.
  • A clinical trial of chemotherapy combined with radiation therapy, with or without laryngectomy.
  • A clinical trial of chemotherapy.
  • A clinical trial of radiosensitizers.
  • A clinical trial of chemoprevention.

If cancer is in the subglottis, treatment may include the following:

  • Laryngectomy plus total thyroidectomy and removal of lymph nodes in the throat, usually with radiation therapy.
  • Radiation therapy.
  • A clinical trial of radiation therapy.
  • A clinical trial of chemotherapy combined with radiation therapy.
  • A clinical trial of chemotherapy.
  • A clinical trial of radiosensitizers.
  • A clinical trial of chemoprevention.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IV laryngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

WebMD Public Information from the National Cancer Institute

Last Updated: September 04, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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