Complementary and alternative medicine (CAM) is a group of diverse medical and health care systems, practices, and products that are not presently considered to be part of conventional medicine (see Question 1).
It is important that the same scientific evaluation that is used to assess conventional approaches be used to evaluate CAM therapies (see Question 4).
The National Cancer Institute and the National Center for Complementary and Alternative Medicine are sponsoring or cosponsoring...
Added text about how emerging evidence suggests that genetic factors may explain the heterogeneity in susceptibility to anthracycline-related cardiac injury, and further study of genetic risk profiling of anthracycline injury is needed to integrate pharmacogenetic data into clinical practice (cited Visscher et al. and Davies as references 26 and 27, respectively).
The Prevalence, Clinical Manifestations, and Risk Factors for Cardiac Toxicity subsection was extensively revised.
Added Campen et al. as reference 66.
Late Effects of the Endocrine System
Added text to state that Childhood Cancer Survivor Study investigators performed a nested case-control study to evaluate the magnitude of risk for thyroid cancer over the therapeutic radiation dose range of pediatric cancers; the risk of thyroid cancer increased with radiation doses up to 20 to 29 Gy, but declined at doses greater than 30 Gy, consistent with a cell-killing effect.
Added text to state that longitudinal decline in body mass index related to substantial decrease in lean mass has been observed among survivors of hematological malignancies treated with allogeneic hematopoietic stem cell transplantation; this finding was largely attributable to total-body irradiation conditioning and severity of chronic graft-versus-host disease (cited Inaba et al. as reference 102).
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September 04, 2014
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