After a gastrointestinal stromal tumor has been diagnosed, tests are done to find out if cancer cells have spread within the gastrointestinal tract or to other parts of the body.
The process used to find out if cancer has spread within the gastrointestinal (GI) tract or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. The following tests and procedures may be used in the staging process:
The risk of ovarian late effects may be increased after treatment with any of the following:
Chemotherapy with alkylating agents, such as cyclophosphamide, mechlorethamine, cisplatin, ifosfamide, lomustine, and especially procarbazine.
Radiation therapy to the abdomen or pelvis. In survivors who had radiation to the abdomen, the damage to the ovaries depends on the radiation dose, age at the time of treatment, and whether all or part of the abdomen received radiation.
Radiation therapy to the abdomen or pelvis together with alkylating agents.
Radiation therapy to the brain and spinal cord.
Total-body irradiation (TBI) before a stem cell transplant. In survivors who had TBI, the damage to the ovaries is greatest in survivors who had not reached puberty at the time of treatment.