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Cancer Health Center

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Nasopharyngeal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Nasopharyngeal Cancer

Although a wide variety of malignant tumors may arise in the nasopharynx, only squamous cell carcinoma is considered in this discussion because management of the other types varies substantially with histology. Subdivisions of squamous cell carcinoma in this site include the following:

World Health Organization (WHO) histopathological grading system describes three types of nasopharyngeal cancer:

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General Information About Small Intestine Cancer

Incidence and Mortality Estimated new cases and deaths from small intestine cancer in the United States in 2014:[1] New cases: 9,160. Deaths: 1,210. Adenocarcinoma, lymphoma, sarcoma, and carcinoid tumors account for the majority of small intestine malignancies, which, as a whole, account for only 1% to 2% of all gastrointestinal malignancies.[2,3,4,5] Follow-up and Survivorship As in other gastrointestinal malignancies, the predominant modality of treatment is surgery when...

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  1. Keratinizing squamous cell carcinoma.
  2. Nonkeratinizing squamous cell carcinoma.
  3. Undifferentiated carcinoma (most common subtype).

Previous subdivisions of nasopharyngeal carcinoma included lymphoepithelioma, which is now classified as WHO grade III characterized by lymphoid infiltrate.[1]

WHO grade I-type cancer accounts for 20% of cases in United States and is associated with alcohol and tobacco use; WHO grade II and III represent the endemic form seen in Southern China.

The presence of keratin has been associated with reduced local control and survival.

References:

  1. Shanmugaratnam K, Sobin L: Histological Typing of Upper Respiratory Tract Tumours. Geneva: World Health Organization, 1978. International Histologic Classification of Tumours: No. 19.

This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

WebMD Public Information from the National Cancer Institute

Last Updated: 8/, 015
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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