Standard Treatment Options
Recurrence of Ewing sarcoma is most common within 2 years of initial diagnosis (approximately 80%).[1,2] However, late relapses occurring more than 5 years from initial diagnosis are more common in Ewing sarcoma (13%; 95% confidence interval, 9.4–16.5) than in other pediatric solid tumors. The overall prognosis for patients with recurrent Ewing sarcoma is poor; 5-year survival following recurrence is approximately 10% to 15%.[2,4,5]; [Level of evidence: 3iiA]...
Radiation therapy followed by surgery to remove the lymph nodes.
Surgery to remove the lymph nodes, with or without radiation therapy.
A clinical trial of new types of treatment.
See the PDQ summary on Metastatic Squamous Neck Cancer with Occult Primary Treatment for more information.
Poorly Differentiated Carcinomas
Cancer cells that are poorly differentiated look very different from normal cells. The type of cell they came from is not known. Treatment of poorly differentiated carcinoma of unknown primary, including tumors in the neuroendocrine system (the part of the brain that controls hormone -producing glands throughout the body) may include the following: