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Nausea and Vomiting (PDQ®): Supportive care - Patient Information [NCI] - Causes

Chemotherapy and radiation therapy are the most common causes of nausea and vomiting in patients being treated for cancer.

Nausea is controlled by a part of the central nervous system that controls involuntary body functions (like the heart beating). Vomiting is a reflex controlled by a vomiting center in the brain. Vomiting can be triggered by smell, taste, anxiety, pain, motion, poor blood flow, irritation, or changes in the body caused by inflammation.

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About This PDQ Summary

Purpose of This Summary This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about treatment of plasma cell neoplasms (including multiple myeloma). It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. Reviewers and Updates This summary is reviewed regularly and updated as necessary...

Read the About This PDQ Summary article > >

The most common causes of nausea and vomiting are:

  • Chemotherapy.
  • Radiation therapy to the gastrointestinal (GI) tract, liver, or brain.

Many factors increase the risk for nausea and vomiting.

Nausea and vomiting are more likely if the patient:

  • Had severe or frequent periods of nausea and vomiting after past chemotherapy sessions.
  • Is female.
  • Is younger than 50 years.
  • Has a fluid and/or electrolyte imbalance (dehydration, too much calcium in the blood, or too much fluid in the body's tissues).
  • Has a tumor in the GI tract, liver, or brain.
  • Has constipation.
  • Is receiving certain drugs, such as opioids (pain medicine).
  • Has an infection or blood poisoning.
  • Has kidney disease.
  • Has anxiety.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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