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Childhood Extracranial Germ Cell Tumors Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Childhood Extracranial Germ Cell Tumors

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Stage III

cdr0000415526.jpg
Pea, peanut, walnut, and lime show tumor sizes.

In stage III, cancer is found in one or both ovaries and has spread to other parts of the abdomen. Stage III is divided into stage IIIA, stage IIIB, and stage IIIC as follows:

  • Stage IIIA: The tumor is found only in the pelvis, but cancer cells that only can be seen with a microscope have spread to the surface of the peritoneum (tissue that lines the abdominal wall and covers most of the organs in the abdomen) or to the small bowel.
  • Stage IIIB: Cancer has spread to the peritoneum but is 2 centimeters or smaller in diameter.
  • Stage IIIC: Cancer has spread to the peritoneum and is larger than 2 centimeters in diameter and/or has spread to lymph nodes in the abdomen.

Cancer that has spread to the surface of the liver is also considered stage III disease.

Stage IV

In stage IV, cancer is found in one or both ovaries and has metastasized (spread) beyond the abdomen to other parts of the body.

Cancer that has spread to tissues in the liver is also considered stage IV disease.

The following stages are commonly used for extragonadal extracranial germ cell tumors:

Stage I

In stage I, the cancer is in one place and can be completely removed by surgery. For tumors at the base of the tailbone, the cancer and tailbone are completed removed by surgery. Tumor marker levels return to normal after surgery.

Stage II

In stage II, the cancer has spread to nearby tissues and/or lymph nodes and is not completely removed by surgery. The cancer remaining after surgery can be seen with a microscope only. Tumor marker levels do not return to normal after surgery and may increase.

Stage III

In stage III, one of the following is true:

  • The cancer is not completely removed by surgery. The cancer remaining after surgery can be seen without a microscope.
  • The cancer has spread to lymph nodes and is larger than 2 centimeters in diameter.

Stage IV

In stage IV, the cancer has spread to distant parts of the body, including the liver.

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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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