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Anal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Anal Cancer

Squamous cell (epidermoid) carcinomas make up the majority of all primary cancers of the anus. The important subset of cloacogenic (basaloid transitional cell) tumors constitutes the remainder. These two histologic variants are associated with human papillomavirus infection.[1] Adenocarcinomas from anal glands or fistulae formation and melanomas are rare. Treatment of anal melanoma is not included in this summary.

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Standard Treatment Options for Extramedullary Plasmacytoma Standard treatment options for extramedullary plasmacytoma include the following: Radiation therapy to the isolated lesion with fields that cover the regional lymph nodes, if possible.[1,2] In some cases, surgical resection may be considered, but it is usually followed by radiation therapy.[2] If the monoclonal (or myeloma) protein (M protein) persists or reappears, the patient may need further radiation therapy. In...

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  1. Palefsky JM, Holly EA, Gonzales J, et al.: Detection of human papillomavirus DNA in anal intraepithelial neoplasia and anal cancer. Cancer Res 51 (3): 1014-9, 1991.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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