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Anal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Anal Cancer

Squamous cell (epidermoid) carcinomas make up the majority of all primary cancers of the anus. The important subset of cloacogenic (basaloid transitional cell) tumors constitutes the remainder. These two histologic variants are associated with human papillomavirus infection.[1] Adenocarcinomas from anal glands or fistulae formation and melanomas are rare. Treatment of anal melanoma is not included in this summary.

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General Information About Adult Soft Tissue Sarcoma

Incidence and Mortality Estimated new cases and deaths from soft tissue sarcoma in the United States in 2013:[1] New cases: 11,410. Deaths: 4,390. Soft tissue sarcomas are malignant tumors that arise in any of the mesodermal tissues of the extremities (50%), trunk and retroperitoneum (40%), or head and neck (10%). The reported international incidence rates range from 1.8 to 5 per 100,000 per year.[2] Risk Factors and Genetic Factors The risk of sporadic soft tissue sarcomas...

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  1. Palefsky JM, Holly EA, Gonzales J, et al.: Detection of human papillomavirus DNA in anal intraepithelial neoplasia and anal cancer. Cancer Res 51 (3): 1014-9, 1991.
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Last Updated: February 25, 2014
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