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Testicular Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Testicular Cancer

Note: This Stage Information section has been updated to include information from the 7th edition (2010) of the American Joint Committee on Cancer's AJCC Cancer Staging Manual. The PDQ Adult Treatment Editorial Board, which is responsible for maintaining this summary, is currently reviewing the new staging categories to determine whether additional changes need to be made to other parts of the summary. Any necessary changes will be made as soon as possible.

Definitions of TNM

The American Joint Committee on Cancer (AJCC) has designated staging by TNM classification to define testicular cancer.[1]

Table 1. Primary Tumor (T)a,b,c

a Reprinted with permission from AJCC: Testis. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 469-78.
b The extent of primary tumor is usually classified after radical orchiectomy, and for this reason, apathologic stage is assigned.
c Except for pTis and pT4, extent of primary tumor is classified by radical orchiectomy. TX may be used for other categories in the absence of radical orchiectomy.
pTXPrimary tumor cannot be assessed.
pT0No evidence of primary tumor (e.g., histologic scar in testis).
pTisIntratubular germ cell neoplasia (carcinoma in situ).
pT1Tumor limited to the testis and epididymis without vascular/lymphatic invasion; tumor may invade into the tunica albuginea but not the tunica vaginalis.
pT2Tumor limited to the testis and epididymis with vascular/lymphatic invasion, or tumor extending through the tunica albuginea with involvement of the tunica vaginalis.
pT3Tumor invades the spermatic cord with or without vascular/lymphatic invasion.
pT4Tumor invades the scrotum with or without vascular/lymphatic invasion.

Table 2. Regional Lymph Nodes (N)a

a Reprinted with permission from AJCC: Testis. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 469-78.
Clinical
NXRegional lymph nodes cannot be assessed.
N0No regional lymph node metastasis.
N1Metastasis with a lymph node mass ≤2 cm in greatest dimension; or multiple lymph nodes, none >2 cm in greatest dimension.
N2Metastasis with a lymph node mass >2 cm but not >5 cm in greatest dimension; or multiple lymph nodes, any one mass >2 cm but not >5 cm in greatest dimension.
N3Metastasis with a lymph node mass >5 cm in greatest dimension.
Pathologic (pN)
pNXRegional lymph nodes cannot be assessed.
pN0No regional lymph node metastasis.
pN1Metastasis with a lymph node mass ≤2 cm in greatest dimension and ≤5 nodes positive, none >2 cm in greatest dimension.
pN2Metastasis with a lymph node mass >2 cm but not >5 cm in greatest dimension; or >5 nodes positive, none >5 cm; or evidence of extranodal extension of tumor.
pN3Metastasis with a lymph node mass >5 cm in greatest dimension.
1|2|3

WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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