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Stage Information for Oropharyngeal Cancer

    Table 2. Regional Lymph Nodes (N)a,b

    a Reprinted with permission from AJCC: Pharynx. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 41-56.
    b Metastases at level VII are considered regional lymph node metastases.
    NXRegional lymph nodes cannot be assessed.
    N0No regional lymph node metastasis.
    N1Metastasis in a single ipsilateral lymph node, ≤3 cm in greatest dimension.
    N2Metastasis in a single ipsilateral lymph node, >3 cm but ≤6 cm in greatest dimension, or metastasis in multiple ipsilateral lymph nodes, ≤6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, ≤6 cm in greatest dimension.
    N2aMetastasis in a single ipsilateral lymph node >3 cm but ≤6 cm in greatest dimension.
    N2bMetastases in multiple ipsilateral lymph nodes, ≤6 cm in greatest dimension.
    N2cMetastases in bilateral or contralateral lymph nodes, ≤6 cm in greatest dimension.
    N3Metastasis in a lymph node >6 cm in greatest dimension.

    Table 3. Distant Metastasis (M)a

    a Reprinted with permission from AJCC: Pharynx. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 41-56.
    M0No distant metastasis.
    M1Distant metastasis.

    Table 4. Anatomic Stage/Prognostic Groupsa

    StageTNM
    a Reprinted with permission from AJCC: Pharynx. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 41-56.
    0TisN0M0
    IT1N0M0
    IIT2N0M0
    IIIT3N0M0
    T1N1M0
    T2N1M0
    T3N1M0
    IVAT4aN0M0
    T4aN1M0
    T1N2M0
    T2N2M0
    T3N2M0
    T4aN2M0
    IVBT4bAny NM0
    Any TN3M0
    IVCAny TAny NM1

    References:

    1. Weber AL, Romo L, Hashmi S: Malignant tumors of the oral cavity and oropharynx: clinical, pathologic, and radiologic evaluation. Neuroimaging Clin N Am 13 (3): 443-64, 2003.
    2. Wong RJ, Lin DT, Schöder H, et al.: Diagnostic and prognostic value of [(18)F]fluorodeoxyglucose positron emission tomography for recurrent head and neck squamous cell carcinoma. J Clin Oncol 20 (20): 4199-208, 2002.
    3. Pharynx. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 41-56.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: February 25, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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