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Cellular Classification of Ovarian Germ Cell Tumors

    The following histologic subtypes have been described.[1,2]

    • Dysgerminoma.
    • Other germ cell tumors:
      • Endodermal sinus tumor (rare subtypes are hepatoid and intestinal).[1]
      • Embryonal carcinoma.
      • Polyembryoma.
      • Choriocarcinoma.
      • Teratoma:
        • Immature.
        • Mature:
          • Solid.
          • Cystic:
            • Dermoid cyst (mature cystic teratoma).
            • Dermoid cyst with malignant transformation.
        • Monodermal and highly specialized:
          • Struma ovarii.
          • Carcinoid.
          • Struma ovarii and carcinoid.
          • Others (e.g., malignant neuroectodermal and ependymoma).
      • Mixed forms.

    References:

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    1. Gershenson DM: Update on malignant ovarian germ cell tumors. Cancer 71 (4 Suppl): 1581-90, 1993.
    2. Serov SF, Scully RE, Robin IH: International Histologic Classification of Tumours: No. 9. Histological Typing of Ovarian Tumours. Geneva: World Health Organization, 1973.

      WebMD Public Information from the National Cancer Institute

      Last Updated: February 25, 2014
      This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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