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Cellular Classification of Ovarian Germ Cell Tumors

    The following histologic subtypes have been described.[1,2]

    • Dysgerminoma.
    • Other germ cell tumors:
      • Endodermal sinus tumor (rare subtypes are hepatoid and intestinal).[1]
      • Embryonal carcinoma.
      • Polyembryoma.
      • Choriocarcinoma.
      • Teratoma:
        • Immature.
        • Mature:
          • Solid.
          • Cystic:
            • Dermoid cyst (mature cystic teratoma).
            • Dermoid cyst with malignant transformation.
        • Monodermal and highly specialized:
          • Struma ovarii.
          • Carcinoid.
          • Struma ovarii and carcinoid.
          • Others (e.g., malignant neuroectodermal and ependymoma).
      • Mixed forms.

    References:

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    1. Gershenson DM: Update on malignant ovarian germ cell tumors. Cancer 71 (4 Suppl): 1581-90, 1993.
    2. Serov SF, Scully RE, Robin IH: International Histologic Classification of Tumours: No. 9. Histological Typing of Ovarian Tumours. Geneva: World Health Organization, 1973.

      This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

      WebMD Public Information from the National Cancer Institute

      Last Updated: February 25, 2014
      This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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