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Treatment Options for Adult Hodgkin Lymphoma

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    Advanced Unfavorable Hodgkin Lymphoma

    Treatment of advanced unfavorable Hodgkin lymphoma may include the following:

    • Combination chemotherapy.
    • Clinical trials of new combinations of chemotherapy.
    • A clinical trial of high-dose chemotherapy and stem cell transplant using the patient's own stem cells.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III adult Hodgkin lymphoma and stage IV adult Hodgkin lymphoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Recurrent Adult Hodgkin Lymphoma

    Treatment of recurrent Hodgkin lymphoma may include the following:

    • Combination chemotherapy.
    • Combination chemotherapy followed by high-dose chemotherapy and stem cell transplant with or without radiation therapy.
    • Radiation therapy with or without chemotherapy.
    • Chemotherapy as palliative therapy to relieve symptoms and improve quality of life.
    • A clinical trial of high-dose chemotherapy and stem cell transplant.
    • A clinical trial of lower-dose chemotherapy and radiation therapy followed by stem cell transplant.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent adult Hodgkin lymphoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Hodgkin Lymphoma During Pregnancy

    Hodgkin Lymphoma During the First Trimester of Pregnancy

    When Hodgkin lymphoma is diagnosed in the first trimester of pregnancy, it does not necessarily mean that the woman will be advised to end the pregnancy. Each woman's treatment will depend on the stage of the lymphoma, how fast it is growing, and her wishes. For women who choose to continue the pregnancy, treatment of Hodgkin lymphoma during the first trimester of pregnancy may include the following:

    • Watchful waiting when the cancer is above the diaphragm and is slow-growing. Delivery may be induced when the fetus is 32 to 36 weeks old so the mother can begin treatment.
    • Radiation therapy above the diaphragm. (A lead shield is used to protect the fetus from the radiation as much as possible.)
    • Systemic chemotherapy using one or more drugs.
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