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Childhood Hodgkin Lymphoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Childhood Hodgkin Lymphoma

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Stages of childhood Hodgkin lymphoma may include A, B, E, and S.

Childhood Hodgkin lymphoma may be described as follows:

  • A: The patient does not have fever, weight loss, or night sweats.
  • B: The patient has B symptoms (fever, weight loss, and night sweats).
  • E: Cancer is found in an organ or tissue that is not part of the lymph system but which may be next to an involved area of the lymph system.
  • S: Cancer is found in the spleen.

The following stages are used for childhood Hodgkin lymphoma:

Stage I

cdr0000648701.jpg
Stage I childhood Hodgkin lymphoma. Cancer is found in one or more lymph nodes in one lymph node group. In stage IE (not shown), cancer is found outside the lymph nodes in one organ or area.

Stage I is divided into stage I and stage IE.

  • Stage I: Cancer is found in one of the following places in the lymph system:
    • One or more lymph nodes in one lymph node group.
    • Waldeyer's ring.
    • Thymus.
    • Spleen.
  • Stage IE: Cancer is found outside the lymph system in one organ or area.

Stage II

Stage II is divided into stage II and stage IIE.


  • cdr0000648702.jpg
    Stage II childhood Hodgkin lymphoma. Cancer is found in two or more lymph node groups, and both are either above (a) or below (b) the diaphragm. Stage II: Cancer is found in two or more lymph node groups either above or below the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen).

  • cdr0000648703.jpg
    Stage IIE childhood Hodgkin lymphoma. Cancer is found in one or more lymph node groups above or below the diaphragm and outside the lymph nodes in a nearby organ or area (a). Stage IIE: Cancer is found in one or more lymph node groups either above or below the diaphragm and outside the lymph nodes in a nearby organ or area.

Stage III

cdr0000648704.jpg
Stage III childhood Hodgkin lymphoma. Cancer is found in one or more lymph node groups above and below the diaphragm (a). In stage IIIE, cancer is found in lymph node groups above and below the diaphragm and outside the lymph nodes in a nearby organ or area (b). In stage IIIS, cancer is found in lymph node groups above and below the diaphragm (a) and in the spleen (c). In stage IIIS plus E, cancer is found in lymph node groups above and below the diaphragm, outside the lymph nodes in a nearby organ or area (b), and in the spleen (c).

Stage III is divided into stage III, stage IIIE, stage IIIS, and stage IIIE,S.

  • Stage III: Cancer is found in lymph node groups above and below the diaphragm (the thin muscle below the lungs that helps breathing and separates the chest from the abdomen).
  • Stage IIIE: Cancer is found in lymph node groups above and below the diaphragm and outside the lymph nodes in a nearby organ or area.
  • Stage IIIS: Cancer is found in lymph node groups above and below the diaphragm, and in the spleen.
  • Stage IIIE,S: Cancer is found in lymph node groups above and below the diaphragm, outside the lymph nodes in a nearby organ or area, and in the spleen.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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