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Treatment Options for Childhood Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Juvenile Myelomonocytic Leukemia

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    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with childhood chronic myelogenous leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Juvenile Myelomonocytic Leukemia

    Treatment of juvenile myelomonocytic leukemia (JMML) is usually stem cell transplant. If JMML recurs after stem cell transplant, a second stem cell transplant may be done.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with juvenile myelomonocytic leukemia. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Transient Myeloproliferative Disorder

    Transient myeloproliferative disorder (TMD) usually goes away on its own. For TMD that does not go away on its own, treatment may include the following:

    • Transfusion therapy.
    • Leukapheresis.
    • Chemotherapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with acute myeloid leukemia/transient myeloproliferative disorder. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Myelodysplastic Syndromes

    Treatment of myelodysplastic syndromes (MDS) may include the following:

    • Watchful waiting.
    • Stem cell transplant.
    • Combination chemotherapy.
    • Lenalidomide therapy.
    • A clinical trial of stem cell transplant using lower doses of chemotherapy.
    • A clinical trial of a new anticancer drug or targeted therapy.

    Supportive care treatments are used to manage problems caused by the disease, such as infection, bleeding, and anemia.

    If the MDS progresses to acute myeloid leukemia (AML), treatment will be the same as treatment for the newly diagnosed patient with AML.

    Treatment of therapy-related MDS is usually the same as for newly diagnosed AML, followed by stem cell transplant.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with childhood myelodysplastic syndromes. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: February 25, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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