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Childhood Liver Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Childhood Liver Cancer

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Treatment of postsurgically-staged stage IV hepatocellular carcinoma may be combination chemotherapy to shrink the tumor, followed by surgery to remove as much of the tumor as possible.

Undifferentiated Embryonal Sarcoma of the Liver

Treatment of undifferentiated embryonal sarcoma of the liver may include the following:

  • Combination chemotherapy to shrink the tumor, followed by surgery to remove as much of the tumor as possible and then more chemotherapy.
  • Surgery to remove the tumor followed by chemotherapy. A second surgery may be done to remove tumor that remains, followed by more chemotherapy.
  • Liver transplant if surgery to remove the tumor is not possible.
  • A clinical trial of chemotherapy before or after surgery, and radiation therapy may also be given.

Infantile Choriocarcinoma of the Liver

Treatment of infantile choriocarcinoma may be combination chemotherapy to shrink the tumor, followed by surgery to remove as much of the tumor as possible.

Recurrent Childhood Liver Cancer

Treatment of recurrent hepatoblastoma may include the following:

  • Surgery to remove isolated (single and separate) metastatic tumors.
  • Liver transplant.
  • A clinical trial of a new treatment.

Treatment of recurrent hepatocellular carcinoma may include the following:

  • Chemoembolization of the hepatic artery to shrink the tumor, followed by surgery to remove the tumor.
  • Liver transplant.
  • A clinical trial of targeted therapy.
  • A clinical trial of a new treatment.

Treatment Options in Clinical Trials

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with childhood liver cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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