Selected Vegetables/Sun's Soup (PDQ®): Complementary and alternative medicine - Health Professional Information [NCI] - Human / Clinical Studies
With respect to the third point, it is important to note that results obtained with such highly motivated, self-selected patients might not be typical of those obtained with most patients diagnosed with advanced non-small cell lung cancer.
The developer is currently conducting a phase II clinical trial to determine whether Selected Vegetables/Sun's Soup can improve immune system function in patients with acquired immunodeficiency syndrome. No information is available about the number of patients enrolled in this trial, and preliminary findings have been described for just one patient.
A randomized phase III trial (NCT00246727) of patients with stage IIIB or stage IV non-small cell lung cancer is being conducted. The primary objective is to compare the survival of patients receiving Selected Vegetables Sun's Soup dietary supplement with those receiving a placebo while undergoing treatment with best supportive care (i.e., radiation therapy, surgery, or palliative care).
Reported Use of Selected Vegetables/Sun's Soup as a Treatment for Human Cancera
|Principal Reference Citation||Type of Study/Report||Type of Cancer||No. of Patients: Enrolled; Treated; Controlb||Strongest Benefit Reported||Concurrent Therapyc||Level of Evidence Scored|
|No. = number.|
|a See text and glossary for more details and definitions of terms.|
|b Number of patients treated plus number of patients controlled may not equal number of patients enrolled; number of patients enrolled = number of patients initially recruited/considered by the researchers who conducted a study; number of patients treated = number of enrolled patients who were administered the treatment being studiedAND for whom results were reported; historical control subjects are not included in number of patients enrolled.|
|c Surgery, chemotherapy, radiation therapy,hormone therapy, pleurodesis administered/allowed at same time as treatment with Selected Vegetables/Sun's Soup.|
|d For information about levels of evidence analysis and an explanation of the level of evidence score, seeLevels of Evidence for Human Studies of Cancer Complementary and Alternative Medicine.|
|||Anecdotal report(patent document)||Metastatic kidney or non-small cell lung||4; 4; None||Complete tumor regression, 3 patients||Yes||None|
|||Phase I/II trial||Early non-small cell lung (toxicity study)||5; 5; None||Improved Karnofsky performance status, 4 patients||Yes||None|
|||Nonconsecutive case series||Advanced non-small cell lung||16; 12; None||Improved median survival||Yes, 10 of 12 evaluated patients||3iiiA|
- Sun AS: Herbal Treatment of Malignancy. US Patent 5437866. August 1, 1995. Washington, DC: US Patent and Trademark Office, 1995. Available online. Last accessed January 10, 2013.
- Sun AS, Ostadal O, Ryznar V, et al.: Phase I/II study of stage III and IV non-small cell lung cancer patients taking a specific dietary supplement. Nutr Cancer 34 (1): 62-9, 1999.
- Sun AS, Yeh HC, Wang LH, et al.: Pilot study of a specific dietary supplement in tumor-bearing mice and in stage IIIB and IV non-small cell lung cancer patients. Nutr Cancer 39 (1): 85-95, 2001.
- Sun Farm Vegetable Soup (SV). Milford, Conn: Sun Farm Corporation, 2000. Available online. Last accessed January 10, 2013.