Cancer Health Center
Treatment Options for Wilms Tumor and Other Childhood Kidney Tumors
A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.
Stage I Wilms Tumor
Treatment of stage I Wilms tumor with favorable histology may include the following:
- Nephrectomy with lymph node removal followed by combination chemotherapy.
- A clinical trial of nephrectomy with lymph node removal, followed by watchful waiting or new combinations of chemotherapy.
Treatment of stage I anaplastic Wilms tumor may include the following:
- Nephrectomy with lymph node removal followed by combination chemotherapy and radiation therapy to the flank (either side of the body between the ribs and hipbone) of the body.
- A clinical trial of nephrectomy with lymph node removal, followed by new combinations of chemotherapy with radiation therapy.
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage I Wilms tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Stage II Wilms Tumor
Treatment of stage II Wilms tumor with favorable histology may include the following:
- Nephrectomy with removal of lymph nodes, followed by combination chemotherapy.
- A clinical trial of nephrectomy with removal of lymph nodes, followed by new combinations of chemotherapy.
Treatment of stage II anaplastic Wilms tumor may include the following:
- Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.
- A clinical trial of nephrectomy with removal of lymph nodes, followed by new combinations of chemotherapy with radiation therapy.
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage II Wilms tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Stage III Wilms Tumor
Treatment of stage III Wilms tumor with favorable histology may include the following:
- Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.
- A clinical trial of nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and new combinations of chemotherapy.
Treatment of stage III anaplastic Wilms tumor may include the following:
- Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.
- Combination chemotherapy given before or after nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen.
- A clinical trial of nephrectomy with removal of lymph nodes, followed by new combinations of chemotherapy with radiation therapy.
WebMD Public Information from the National Cancer Institute
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER
Experts are making great strides in treating cancer. But many of these advances apply only after the cancer has been diagnosed. Now the disease is about to come under attack with a revolutionary tool called a nanoshell. Learn how scientists hope the new technology will detect and destroy cancer cells sooner.
