Langerhans Cell Histiocytosis Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview for LCH
There are different types of treatment for patients with Langerhans cell histiocytosis (LCH).
Different types of treatments are available for patients with LCH. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Whenever possible, patients should take part in a clinical trial in order to receive new types of treatment for LCH.
Stage IV melanoma is defined by the American Joint Committee on Cancer's TNM classification system:
Any T, any N, M1
Treatment Options for Patients With Stage IV and Recurrent Melanoma
Signal transduction inhibitors.BRAF (V-raf murinesarcoma viral oncogene homolog B1) inhibitors (for patients who test positive for the BRAF V600 mutation).
Palliative local therapy.
Clinical trials should be strongly...
Clinical trials are taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Web site. Choosing the most appropriate treatment is a decision that ideally involves the patient, family, and health care team.
Children with LCH should have their treatment planned by a team of health care providers who are experts in treating this disease in children.
Treatment will be overseen by a pediatric oncologist, a doctor who specializes in treating children with cancer. The pediatric oncologist works with other pediatric healthcare providers who are experts in treating children with LCH and who specialize in certain areas of medicine. These may include the following specialists:
Radiation therapy is a treatment that uses high-energy x-rays or other types of radiation to kill cells or keep them from growing. External radiation therapy uses a machine outside the body to send radiation toward the LCH lesion.