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Nutrition in Cancer Care (PDQ®): Supportive care - Patient Information [NCI] - Food and Drug Interactions

Some foods do not mix safely with certain drugs.

Cancer patients may be treated with a number of drugs. Taking certain foods and drugs together may decrease or change how well the drugs work or cause life-threatening side effects. The following table lists some of the food and drug interactions that may occur with certain anticancer drugs:

Drug-Food Interactions

Brand NameGeneric NameFood Interactions
TargretinBexaroteneGrapefruit juice may increase the drug's effects.
FolexMethotrexateAlcoholmay causeliverdamage.
Rheumatrex
MithracinPlicamycinSupplementsofcalciumandvitamin Dmay decrease the drug's effect.
MatulaneProcarbazineAlcohol may cause headache, trouble breathing, flushed skin,nausea, orvomiting,Caffeinemay raiseblood pressure.
TemodarTemozolomideFood may slow or decrease the drug's effect.

Talk with your doctor about possible food and drug interactions.

Some herbal supplements do not mix safely with certain drugs or foods.

Taking some herbal supplements with certain foods and drugs may change how well cancer treatment works or cause life-threatening side effects. Talk with your doctor about how herbal supplements may affect your cancer treatment.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: September 04, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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