No clinical studies (i.e., clinical trials, case series, or case reports) have been reported in peer-reviewed scientific journals to support the safety or the efficacy of 714-X. A number of anecdotal reports and testimonials have been published in newspapers and other nonmedical literature. The producers of 714-X state that they have tried to document the long-term experience of patients treated with this compound, but they have encountered difficulty in obtaining information from patients and their...
Drugs that help the salivary glands make more saliva.
Treatments to replace minerals lost from teeth by acids in the mouth.
Oral devices need special care during high-dose chemotherapy and/or stem cell transplant.
The following can help in the care and use of dentures, braces, and other oral devices during high-dose chemotherapy or stem cell transplant:
Have brackets, wires, and retainers removed before high-dose chemotherapy begins.
Wear dentures only when eating during the first 3 to 4 weeks after the transplant.
Brush dentures twice a day and rinsing them well.
Soak dentures in an antibacterial solution when they are not being worn.
Clean denture soaking cups and changing denture soaking solution every day.
Remove dentures or other oral devices when cleaning your mouth.
Continue your regular oral care 3 or 4 times a day with dentures or other devices out of the mouth.
If you have mouth sores, avoid using removable oral devices until the sores have healed.
Care of the teeth and gums is important during chemotherapy or stem cell transplant.
Talk to your doctor or dentist about the best way to take care of your mouth during high-dose chemotherapy and stem cell transplant. Careful brushing and flossing may help prevent infection of oral tissues. The following may help prevent infection and relieve discomfort of oral in tissues:
Brush teeth with a soft-bristle brush 2 to 3 times a day. Be sure to brush the area where the teeth meet the gums.
Rinse the toothbrush in hot water every 15 to 30 seconds to keep the bristles soft.
Rinse your mouth 3 or 4 times while brushing.
Avoid rinses that have alcohol in them.
Use a mild-tasting toothpaste.
Let the toothbrush air-dry between uses.
Floss according to your doctor's or dentist's directions.
Clean the mouth after meals.
Use foam swabs to clean the tongue and roof of the mouth.
Avoid the following:
Foods that are spicy or acidic.
"Hard" foods that could irritate or break the skin in your mouth, such as chips.