Skip to content

Cancer Health Center

Font Size

Paranasal Sinus and Nasal Cavity Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage II Paranasal Sinus and Nasal Cavity Cancer

Stage II disease includes small and moderately advanced lesions.

Standard treatment options:

Recommended Related to Cancer

I Had the Cancer No One Talks About

By Darci Picoult It began with a bump. The size of a pinhead. Innocuous. An innocuous little pinhead of a bump on my vulva. Given that my gynecologist said the bump was probably nothing, I laughed it off. Which, in turn, made my bump mad. Very mad. It wanted my attention. And so it grew. I smeared it in medicine. It grew more. More medicine. More growth. Hanukkah came. Then Christmas. A war raged between us. I went to battle in the middle of the night with salt baths and creams. Prayed for its departure...

Read the I Had the Cancer No One Talks About article > >

  1. For maxillary sinus tumors:
    • Surgical resection with high-dose preoperative or postoperative radiation therapy.
  2. For ethmoid sinus tumors (lesions are usually extensive when diagnosed):[1,2,3]
    • Generally, external-beam radiation therapy alone is used and produces better overall results than surgery.
    • Well-localized lesions can be resected, but resection of the ethmoids, maxilla, and orbit, often with a combined neurosurgical sinus craniofacial approach, is generally required.
    • If surgery can be done with good functional and cosmetic results, postoperative radiation therapy should be given even with clear surgical margins.
  3. For sphenoid sinus tumors:
    • Treatment is the same as for nasopharyngeal cancers, primarily radiation therapy. (Refer to the Stage II Nasopharyngeal Cancer section in the PDQ summary on Nasopharyngeal Cancer Treatment for more information.) Concomitant chemotherapy and radiation therapy may be considered.
  4. For nasal cavity tumors (squamous cell carcinomas), treatment preferences are either surgery or radiation therapy, which have equal cure rates:[4]
    • Surgery or radiation therapy for tumors of the septum.
    • Radiation therapy for tumors of the lateral and superior walls. Concomitant chemotherapy and radiation therapy may be considered.
    • Surgery plus radiation therapy for tumors of the septal and lateral walls.[5]
  5. For inverting papilloma:
    • Surgical excision.
    • Re-excision for surgery failures.
    • Radiation therapy for radical surgery failures may eventually be necessary.
  6. For melanomas and sarcomas:
    • Surgical excision if possible.
    • Combined surgery, radiation, and chemotherapy are recommended for rhabdomyosarcoma.
  7. For midline granuloma:
    • Radiation therapy to nasal cavity and paranasal sinuses.
  8. For nasal vestibule tumors:
    • Surgery or radiation therapy may be performed. If tumors are extremely small, surgery is preferred provided that no deformity is expected and a need for reconstruction is not anticipated. Radiation therapy is preferred for other small lesions.[6,7] Treatment of the neck should be considered.

Current Clinical Trials

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II paranasal sinus and nasal cavity cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

    1|2
    Next Article:

    Today on WebMD

    Colorectal cancer cells
    A common one in both men and women.
    Lung cancer xray
    See it in pictures, plus read the facts.
     
    sauteed cherry tomatoes
    Fight cancer one plate at a time.
    Ovarian cancer illustration
    Real Cancer Perspectives
     
    Jennifer Goodman Linn self-portrait
    Blog
    what is your cancer risk
    HEALTH CHECK
     
    colorectal cancer treatment advances
    Video
    breast cancer overview slideshow
    SLIDESHOW
     
    prostate cancer overview
    SLIDESHOW
    lung cancer overview slideshow
    SLIDESHOW
     
    ovarian cancer overview slideshow
    SLIDESHOW
    Actor Michael Douglas
    Article