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Paranasal Sinus and Nasal Cavity Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Paranasal Sinus and Nasal Cavity Cancer

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Stage III

In stage III, cancer has spread to any of the following:

  • Bone at the back of the maxillary sinus.
  • Tissues under the skin.
  • The eye socket.
  • The base of the skull.
  • The ethmoid sinuses.

or

Cancer has spread to one lymph node on the same side of the neck as the cancer and the lymph node is 3 centimeters or smaller. Cancer has also spread to any of the following:

  • The lining of the maxillary sinus.
  • Bones around the maxillary sinus, including the roof of the mouth and the nose.
  • Tissues under the skin.
  • The eye socket.
  • The base of the skull.
  • The ethmoid sinuses.

Stage IV

Stage IV is divided into stage IVA, IVB, and IVC.

Stage IVA

In stage IVA, cancer has spread either:

  • to one lymph node on the same side of the neck as the cancer and the lymph node is larger than 3 centimeters but not larger than 6 centimeters; or
  • to more than one lymph node on the same side of the neck as the original tumor and the lymph nodes are not larger than 6 centimeters; or
  • to lymph nodes on the opposite side of the neck as the original tumor or on both sides of the neck, and the lymph nodes are not larger than 6 centimeters.

and cancer has spread to any of the following:

  • The lining of the maxillary sinus.
  • Bones around the maxillary sinus, including the roof of the mouth and the nose.
  • Tissues under the skin.
  • The eye socket.
  • The base of the skull.
  • The ethmoid sinuses.

or

Cancer has spread to any of the following:

  • The front of the eye.
  • The skin of the cheek.
  • The base of the skull.
  • Behind the jaw.
  • The bone between the eyes.
  • The sphenoid or frontal sinuses.

and cancer may also have spread to one or more lymph nodes 6 centimeters or smaller, anywhere in the neck.

Stage IVB

In stage IVB, cancer has spread to any of the following:

  • The back of the eye.
  • The brain.
  • The middle parts of the skull.
  • The nerves in the head that go to the brain.
  • The upper part of the throat behind the nose.
  • The base of the skull.
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