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Cancer Health Center

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Penile Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

Stage 0 (Carcinoma in Situ)

Treatment of stage 0 may be one of the following:

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  • Mohs microsurgery.
  • Topical chemotherapy.
  • Topical biologic therapy.
  • Laser surgery.
  • Cryosurgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 penile cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage I Penile Cancer

If the cancer is only in the foreskin, wide local excision and circumcision may be the only treatment needed.

Treatment of stage I penile cancer may include the following:

  • Surgery (partial or total penectomy with or without removal of lymph nodes in the groin.
  • External or internal radiation therapy.
  • Mohs microsurgery.
  • A clinical trial of laser therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I penile cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage II Penile Cancer

Treatment of stage II penile cancer may include the following:

  • Surgery (partial or total penectomy, with or without removal of lymph nodes in the groin).
  • External or internal radiation therapy followed by surgery.
  • A clinical trial of sentinel lymph node biopsy followed by surgery.
  • A clinical trial of laser surgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II penile cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

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