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Primary CNS Lymphoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Primary CNS Lymphoma

Primary CNS Lymphoma Not Related to AIDS

Treatment of primary central nervous system (CNS) lymphoma in patients who do not have AIDS may include the following:

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  • Chemotherapy.
  • Chemotherapy followed by radiation therapy.
  • Whole brain radiation therapy.
  • A clinical trial of high-dose chemotherapy with stem cell transplant.

Primary CNS Lymphoma Related to AIDS

Treatment of primary central nervous system (CNS) lymphoma in patients who do have AIDS may include the following:

  • Steroids with or without radiation therapy.
  • Radiation therapy alone.
  • Chemotherapy followed by radiation therapy.

Treatment of primary CNS lymphoma is different in patients with AIDS because the treatment side effects may be more severe. (See the PDQ summary on AIDS-Related Lymphoma Treatment for more information).

Recurrent Primary CNS Lymphoma

Treatment of recurrent primary central nervous system (CNS) lymphoma may include the following:

  • Chemotherapy or radiation therapy (if not received in earlier treatment).
  • A clinical trial of a new drug or treatment schedule.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with primary central nervous system non-Hodgkin lymphoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: September 04, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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