Skip to content
My WebMD Sign In, Sign Up

Cancer Health Center

Font Size

Renal Cell Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage II Renal Cell Cancer

Stage II renal cell cancer is defined by the American Joint Committee on Cancer's TNM classification system:

  • T2, N0, M0

Radical resection is the accepted, often curative, therapy for stage II renal cell cancer. The operation includes removal of the kidney, adrenal gland, perirenal fat, and Gerota fascia, with or without a regional lymph node dissection.[2] Lymphadenectomy is commonly employed, but its effectiveness has not been definitively proven. External-beam radiation therapy (EBRT) has been given before or after nephrectomy without conclusive evidence that this improves survival when compared with the results of surgery alone; however, it may be of benefit in selected patients with more extensive tumors. In patients who are not candidates for surgery, arterial embolization can provide palliation.

Recommended Related to Kidney Cancer

To Learn More About Transitional Cell Cancer of the Renal Pelvis and Ureter

For more information from the National Cancer Institute about transitional cell cancer of the renal pelvis and ureter, see the following: Transitional Cell Cancer (Kidney/Ureter) Home Page Smoking Home Page (Includes help with quitting) For general cancer information and other resources from the National Cancer Institute, see the following: What You Need to Know About™ Cancer Understanding Cancer Series: Cancer Cancer Staging Chemotherapy and You: Support for People With...

Read the To Learn More About Transitional Cell Cancer of the Renal Pelvis and Ureter article > >

Standard treatment options:

  1. Radical nephrectomy.[3]
  2. Nephrectomy before or after EBRT (selected patients).[3]
  3. Partial nephrectomy (selected patients).[3]
  4. EBRT (palliative).[3]
  5. Arterial embolization (palliative).
  6. Clinical trials.

Current Clinical Trials

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II renal cell cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

References:

  1. Kidney. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 479-89.
  2. Phillips E, Messing EM: Role of lymphadenectomy in the treatment of renal cell carcinoma. Urology 41 (1): 9-15, 1993.
  3. deKernion JB, Berry D: The diagnosis and treatment of renal cell carcinoma. Cancer 45 (7 Suppl): 1947-56, 1980.
1

WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Today on WebMD

Building a Support System
Blog
cancer fighting foods
SLIDESHOW
 
precancerous lesions slideshow
SLIDESHOW
quit smoking tips
SLIDESHOW
 
Jennifer Goodman Linn self-portrait
Blog
what is your cancer risk
HEALTH CHECK
 
colorectal cancer treatment advances
Video
breast cancer overview slideshow
SLIDESHOW
 
prostate cancer overview
SLIDESHOW
lung cancer overview slideshow
SLIDESHOW
 
ovarian cancer overview slideshow
SLIDESHOW
Actor Michael Douglas
Article