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Cancer Health Center

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Salivary Gland Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

Stage I Salivary Gland Cancer

Treatment for stage I salivary gland cancer depends on whether the cancer is low-grade (slow growing) or high-grade (fast growing).

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General Information About Langerhans Cell Histiocytosis (LCH)

Langerhans cell histiocytosis is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell histiocytosis (LCH) is a rare cancer that begins in LCH cells (a type of dendritic cell which fights infection). Sometimes there are mutations (changes) in LCH cells as they form. These include mutations of the BRAFgene. These changes may make the LCH cells grow and multiply quickly. This causes LCH cells to build up in certain parts of the body,...

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If the cancer is low-grade, treatment may include the following:

If the cancer is high-grade, treatment may include the following:

  • Surgery with or without radiation therapy.
  • A clinical trial of chemotherapy.
  • A clinical trial of a new local therapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I salivary gland cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage II Salivary Gland Cancer

Treatment for stage II salivary gland cancer depends on whether the cancer is low-grade (slow growing) or high-grade (fast growing).

If the cancer is low-grade, treatment may include the following:

  • Surgery with or without radiation therapy.
  • Radiation therapy.
  • Chemotherapy.

If the cancer is high-grade, treatment may include the following:

  • Surgery with or without radiation therapy.
  • Fast neutron or photon-beam radiation therapy.
  • A clinical trial of radiation therapy and/or radiosensitizers.
  • A clinical trial of chemotherapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II salivary gland cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage III Salivary Gland Cancer

Treatment for stage III salivary gland cancer depends on whether the cancer is low-grade (slow growing) or high-grade (fast growing).

If the cancer is low-grade, treatment may include the following:

  • Surgery with or without lymphadenectomy. Radiation therapy may also be given after surgery.
  • Radiation therapy.
  • Fast neutron radiation therapy to lymph nodes with cancer.
  • Chemotherapy.
  • A clinical trial of fast neutron radiation therapy to the tumor.
  • A clinical trial of chemotherapy.
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