Childhood Soft Tissue Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information
Table 2. Frequent Chromosomal Aberrations Seen in Nonrhabdomyosarcomatous STSa continued...
Soft tissue sarcomas in older children and adolescents often behave similarly to those in adult patients.[5,21]
Pediatric patients with unresected localized nonrhabdomyosarcomatous STSs have a poor outcome. Only about one-third of patients treated with multimodality therapy remain disease free.[36,39]; [40,41][Level of evidence: 3iiiA]
In a pooled analysis from U.S. and European pediatric centers, outcome was better for patients who received radiation therapy than for patients who did not, and outcome was better for patients whose tumor-removal procedure was deemed complete than for patients whose tumor removal was incomplete.[Level of evidence: 3iiiA]
Because long-term related morbidity must be minimized while disease-free survival is maximized, the ideal therapy for each patient must be carefully and individually determined utilizing these prognostic factors before initiating therapy for these patients.[18,42,43,44,45,46]
Related Disease Summaries
Refer to the following PDQ summaries for information about other types of sarcoma:
- Childhood Rhabdomyosarcoma Treatment.
- Ewing Sarcoma Treatment (extraosseous Ewing, peripheral neuroepithelioma, and Askin tumors).
- Unusual Cancers of Childhood Treatment (gastrointestinal stromal tumors).
- Adult Soft Tissue Sarcoma Treatment.
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