Skip to content

Cancer Health Center

Font Size

Stomach (Gastric) Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Overview

Note: Separate PDQ summaries on Stomach (Gastric) Cancer Prevention, Gastric Cancer Treatment, and Levels of Evidence for Cancer Screening and Prevention Studies are also available.

Benefits

Recommended Related to Cancer

Overview

This complementary and alternative medicine (CAM) information summary provides an overview of the use of laetrile as a treatment for people with cancer. The summary includes a history of laetrile research, a review of laboratory studies, the results of clinical trials, and possible side effects of laetrile use. This summary contains the following key information: Laetrile is another name for the chemical amygdalin, which is found in the pits of many fruits and in numerous plants. Cyanide...

Read the Overview article > >

Based on fair evidence, screening would not result in a decrease in mortality from gastric cancer in areas with relatively low incidence of the disease, such as the United States.

Magnitude of Effect: Fair evidence for no reduction in mortality.

  • Study Design: Evidence obtained from case-control and cohort studies, primarily from high-risk areas such as Eastern Asia.
  • Internal Validity: Fair.
  • Consistency: Poor in prospective studies.[1]
  • External Validity: Poor. Studies on populations in high-risk areas may not be applicable to low-risk areas such as the United States.

Harms

Based on solid evidence, screening would result in uncommon but serious side effects associated with endoscopy, which may include perforation, cardiopulmonary events, aspiration pneumonia, and bleeding requiring hospitalization.

False-positive tests are also common in association with serum pepsinogen or gastric photofluorography.

Magnitude of Effect: Good evidence for rare but serious harms.

Description of the Evidence

  • Study Design: Evidence obtained from screening programs and from case series.
  • Internal Validity: Fair.
  • Consistency: Inadequate evidence.
  • External Validity: Poor.

References:

  1. Leung WK, Wu MS, Kakugawa Y, et al.: Screening for gastric cancer in Asia: current evidence and practice. Lancet Oncol 9 (3): 279-87, 2008.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: September 04, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    1
    Next Article:

    Today on WebMD

    Colorectal cancer cells
    A common one in both men and women.
    Lung cancer xray
    See it in pictures, plus read the facts.
     
    sauteed cherry tomatoes
    Fight cancer one plate at a time.
    Ovarian cancer illustration
    Real Cancer Perspectives
     
    Jennifer Goodman Linn self-portrait
    Blog
    what is your cancer risk
    HEALTH CHECK
     
    colorectal cancer treatment advances
    Video
    breast cancer overview slideshow
    SLIDESHOW
     
    prostate cancer overview
    SLIDESHOW
    lung cancer overview slideshow
    SLIDESHOW
     
    ovarian cancer overview slideshow
    SLIDESHOW
    Actor Michael Douglas
    Article