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    Testicular Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Testicular Cancer

    Definitions of TNM

    The American Joint Committee on Cancer (AJCC) has designated staging by TNM classification to define testicular cancer.[1]

    Table 1. Primary Tumor (T)a,b,c

    a Reprinted with permission from AJCC: Testis. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 469-78.
    b The extent of primary tumor is usually classified after radical orchiectomy, and for this reason, apathologic stage is assigned.
    c Except for pTis and pT4, extent of primary tumor is classified by radical orchiectomy. TX may be used for other categories in the absence of radical orchiectomy.
    pTX Primary tumor cannot be assessed.
    pT0 No evidence of primary tumor (e.g., histologic scar in testis).
    pTis Intratubular germ cell neoplasia (carcinoma in situ).
    pT1 Tumor limited to the testis and epididymis without vascular/lymphatic invasion; tumor may invade into the tunica albuginea but not the tunica vaginalis.
    pT2 Tumor limited to the testis and epididymis with vascular/lymphatic invasion, or tumor extending through the tunica albuginea with involvement of the tunica vaginalis.
    pT3 Tumor invades the spermatic cord with or without vascular/lymphatic invasion.
    pT4 Tumor invades the scrotum with or without vascular/lymphatic invasion.

    Table 2. Regional Lymph Nodes (N)a

    a Reprinted with permission from AJCC: Testis. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 469-78.
    Clinical
    NX Regional lymph nodes cannot be assessed.
    N0 No regional lymph node metastasis.
    N1 Metastasis with a lymph node mass ≤2 cm in greatest dimension; or multiple lymph nodes, none >2 cm in greatest dimension.
    N2 Metastasis with a lymph node mass >2 cm but not >5 cm in greatest dimension; or multiple lymph nodes, any one mass >2 cm but not >5 cm in greatest dimension.
    N3 Metastasis with a lymph node mass >5 cm in greatest dimension.
    Pathologic (pN)
    pNX Regional lymph nodes cannot be assessed.
    pN0 No regional lymph node metastasis.
    pN1 Metastasis with a lymph node mass ≤2 cm in greatest dimension and ≤5 nodes positive, none >2 cm in greatest dimension.
    pN2 Metastasis with a lymph node mass >2 cm but not >5 cm in greatest dimension; or >5 nodes positive, none >5 cm; or evidence of extranodal extension of tumor.
    pN3 Metastasis with a lymph node mass >5 cm in greatest dimension.
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