Skip to content

    Cancer Health Center

    Font Size
    A
    A
    A

    Vaginal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

    Vaginal Intraepithelial Neoplasia (VAIN)

    Treatment of vaginal intraepithelial neoplasia (VAIN) 1 is usually watchful waiting.

    Recommended Related to Cancer

    Overview

    Hydrazine sulfate is a chemical compound that has been studied as a treatment for cancer and certain side effects caused by cancer (see Question 1). Hydrazine sulfate may block the tumor from taking in glucose, which is a type of sugar that tumor cells need to grow (see Question 3). In randomized clinical trials (a type of research study), hydrazine sulfate did not make tumors shrink or go away. In some randomized trials, however, hydrazine sulfate was reported to be helpful in treating...

    Read the Overview article > >

    Treatment of VAIN 2 and 3 may include the following:

    • Watchful waiting.
    • Laser surgery.
    • Wide local excision, with or without a skin graft.
    • Partial or total vaginectomy, with or without a skin graft.
    • Topical chemotherapy.
    • Internal radiation therapy.
    • A clinical trial of a new topical chemotherapy drug.

    Stage I Vaginal Cancer

    Treatment of stage I squamous cell vaginal cancer may include the following:

    • Internal radiation therapy.
    • External radiation therapy, especially for large tumors or the lymph nodes near tumors in the lower part of the vagina.
    • Wide local excision or vaginectomy with vaginal reconstruction. Radiation therapy may be given after the surgery.
    • Vaginectomy and lymph node dissection, with or without vaginal reconstruction. Radiation therapy may be given after the surgery.

    Treatment of stage I vaginal adenocarcinoma may include the following:

    • Vaginectomy, hysterectomy, and lymph node dissection. This may be followed by vaginal reconstruction and/or radiation therapy.
    • Internal radiation therapy. External radiation therapy may also be given to the lymph nodes near tumors in the lower part of the vagina.
    • A combination of therapies that may include wide local excision with or without lymph node dissection and internal radiation therapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I vaginal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage II Vaginal Cancer

    Treatment of stage II vaginal cancer is the same for squamous cell cancer and adenocarcinoma. Treatment may include the following:

    • Both internal and external radiation therapy to the vagina. External radiation therapy may also be given to the lymph nodes near tumors in the lower part of the vagina.
    • Vaginectomy or pelvic exenteration. Internal and/or external radiation therapy may also be given.
    1 | 2 | 3
    1 | 2 | 3
    Next Article:

    Today on WebMD

    man holding lung xray
    What you need to know.
    stem cells
    How they work for blood cancers.
     
    woman wearing pink ribbon
    Separate fact from fiction.
    Colorectal cancer cells
    Symptoms, screening tests, and more.
     
    Jennifer Goodman Linn self-portrait
    Blog
    what is your cancer risk
    HEALTH CHECK
     
    colorectal cancer treatment advances
    Video
    breast cancer overview slideshow
    SLIDESHOW
     
    prostate cancer overview
    SLIDESHOW
    lung cancer overview slideshow
    SLIDESHOW
     
    ovarian cancer overview slideshow
    SLIDESHOW
    Actor Michael Douglas
    Article