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Vulvar Cancer Treatment (PDQ®) - Treatment Options by Stage

Stage 0 (Carcinoma in Situ)

Treatment of stage 0 may include the following:

Wide local excision and/or laser therapy.
Skinning vulvectomy with or without skin grafting.
Simple vulvectomy.
Topical chemotherapy.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage 0 vulvar cancer.

Stage I Vulvar Cancer

Treatment of stage I vulvar cancer may include the following:

Wide local excision.
Radical local excision with removal of nearby lymph nodes.
Radical vulvectomy and either removal of nearby lymph nodes or radiation therapy to the lymph nodes.
Radiation therapy.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage I vulvar cancer.

Stage II Vulvar Cancer

Treatment of stage II vulvar cancer may include the following:

Modified radical vulvectomy and removal of nearby lymph nodes or radiation therapy to the lymph nodes. Radiation therapy to the area of surgery may also be given.
Radiation therapy.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage II vulvar cancer.

Stage III Vulvar Cancer

Treatment of stage III vulvar cancer may include the following:

Modified radical vulvectomy and removal of nearby lymph nodes, with or without radiation therapy.
Radical vulvectomy and removal of nearby lymph nodes, with or without radiation therapy.
Radiation therapy followed by surgery.
Radiation therapy with or without chemotherapy.
A clinical trial of a new treatment.

Information about ongoing clinical trials is available from the NCI Web site.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage III vulvar cancer.

Stage IV Vulvar Cancer

Treatment of stage IV vulvar cancer may include the following:

Radical vulvectomy and pelvic exenteration.
Radical vulvectomy followed by radiation therapy.
Radiation therapy followed by surgery, with or without chemotherapy.
Radiation therapy with or without chemotherapy.
A clinical trial of a new treatment.

Information about ongoing clinical trials is available from the NCI Web site.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage IV vulvar cancer.

WebMD Public Information from the National Cancer Institute

This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER

Last Updated: September 20, 2007

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