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Vulvar Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Vulvar Intraepithelial Neoplasia (VIN)

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Treatment of vulvar intraepithelial neoplasia (VIN) may include the following:

  • Removal of single lesions or wide local excision.
  • Laser surgery.
  • Ultrasound surgical aspiration.
  • Skinning vulvectomy with or without a skin graft.
  • Biologic therapy with topical imiquimod.

Stage I Vulvar Cancer

Treatment of stage I vulvar cancer may include the following:

  • Wide local excision for lesions that are less than 1 millimeter deep..
  • Radical local excision and removal of nearby lymph nodes.
  • Radical local excision and sentinel lymph node biopsy. If cancer is found in the sentinel lymph node, nearby lymph nodes are also removed.
  • Radiation therapy for patients who cannot have surgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage II Vulvar Cancer

Treatment of stage II vulvar cancer may include the following:

  • Radical local excision and removal of nearby lymph nodes.
  • Modified radical vulvectomy or radical vulvectomy for large tumors. Nearby lymph nodes may be removed. Radiation therapy may be given after surgery.
  • Radical local excision and sentinel lymph node biopsy. If cancer is found in the sentinel lymph node, nearby lymph nodes are also removed.
  • Radiation therapy for patients who cannot have surgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage III Vulvar Cancer

Treatment of stage III vulvar cancer may include the following:

  • Modified radical vulvectomy or radical vulvectomy. Nearby lymph nodes may be removed.Radiation therapy may be given after surgery.
  • Radiation therapy or chemotherapy and radiation therapy followed by surgery.
  • Radiation therapy with or without chemotherapy for patients who cannot have surgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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