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    Vulvar Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Vulvar Cancer

    Presented below is an adaptation of the histologic classification of vulvar disease and precursor lesions of cancer of the vulva developed by the International Society for the Study of Vulvar Disease.[1] This evidence summary deals with vulvar intraepithelial neoplasias (VIN) and invasive carcinomas.

    Non-neoplastic epithelial disorders of skin and mucosa

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    Incidence and Mortality Estimated new cases and deaths from vaginal (and other female genital) cancer in the United States in 2014:[1] New cases: 3,170. Deaths: 880. Carcinomas of the vagina are uncommon tumors comprising about 1% of the cancers that arise in the female genital system.[1,2] Early stage tumors are often curable with local modality therapies, but there is no standard treatment of proven efficacy for metastatic disease. A large proportion (30%-50%) of women with...

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    VIN

    • Usual type (high-grade 2 and 3).
    • Differentiated type (high-grade 3).

    Paget disease of the vulva

    • Characteristic large pale cells in the epithelium and skin adnexa.

    Other histologies

    References:

    1. Sideri M, Jones RW, Wilkinson EJ, et al.: Squamous vulvar intraepithelial neoplasia: 2004 modified terminology, ISSVD Vulvar Oncology Subcommittee. J Reprod Med 50 (11): 807-10, 2005.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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