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    Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Wilms Tumor

    Stage I Wilms Tumor

    Treatment of stage I Wilms tumor with favorable histology may include:

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    • Nephrectomy with removal of lymph nodes followed by combination chemotherapy.
    • A clinical trial of nephrectomy only.

    Treatment of stage I anaplastic Wilms tumor may include:

    • Nephrectomy with removal of lymph nodes followed by combination chemotherapy and radiation therapy to the flank (either side of the body between the ribs and hipbone) of the body.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I Wilms tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your child's doctor about clinical trials that may be right for your child. General information about clinical trials is available from the NCI Web site.

    Stage II Wilms Tumor

    Treatment of stage II Wilms tumor with favorable histology may include:

    • Nephrectomy with removal of lymph nodes, followed by combination chemotherapy.

    Treatment of stage II anaplastic Wilms tumor may include:

    • Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II Wilms tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your child's doctor about clinical trials that may be right for your child. General information about clinical trials is available from the NCI Web site.

    Stage III Wilms Tumor

    Treatment of stage III Wilms tumor with favorable histology may include:

    • Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.

    Treatment of stage III anaplastic Wilms tumor may include:

    • Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.
    • Combination chemotherapy given before nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen.
    • Nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy.
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