Genetic Disorders Directory
Genetic disorders are diseases that are caused by abnormal DNA or mutations. These abnomalities can be small changes to a single gene or be much more complex and affect a chromosome or an entire group of chromosomes. Genetic disorders cause a long list of diseases from cystic fibrosis to being more suseptable to various types of cancers. Find out more about various genetic disorders with articles, news and more.
Nasopharyngeal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI]-Stage Information for Nasopharyngeal Cancer
Staging systems are all clinical staging and are based on the best possible estimate of the extent of disease before treatment.[1,2] Assessment of the primary tumor is based on inspection and palpation, and fiberoptic endoscopic evaluation. The tumor must be confirmed histologically, and any other pathologic data obtained on biopsy may be included. Evaluation of the function of the cranial nerves is especially appropriate for tumors of the nasopharynx. The appropriate nodal drainage areas are examined by careful palpation and radiologic evaluation. The retropharyngeal lymph nodes are the first echelon of drainage.[3,4] Information from diagnostic imaging studies may be used in staging. Magnetic resonance imaging provides additional information to computed tomographic scanning in the evaluation of skull base invasion and intracranial spread. Positron emission tomography scans combined with CT are helpful in radiation treatment planning for target delineation of the primary
Unusual Cancers of Childhood Treatment (PDQ®): Treatment - Patient Information [NCI]-Unusual Cancers of the Head and Neck
Nasopharyngeal CancerNasopharyngeal cancer is a disease in which malignant (cancer) cells form in the lining of the nasal cavity (inside of the nose) and throat. It is rare in children younger than 10 and more common in teenagers.Risk Factors, Symptoms, and Diagnostic and Staging Tests The risk of nasopharyngeal cancer is greatly increased by having an infection with the Epstein-Barr virus (EBV), which infects cells of the immune system.Nasopharyngeal cancer may cause any of the following signs and symptoms. Check with your child's doctor if you see any of the following problems in your child:Painless lumps in the neck.Nosebleeds.Blocked or stuffy nose.Ear infection.Snoring.Problems moving the jaw.Hearing loss.Double vision.Other conditions that are not nasopharyngeal cancer may cause these same symptoms.When nasopharyngeal is diagnosed, it usually has already spread to lymph nodes in the neck and bones of the skull. It may also spread to the nose, mouth, throat, bones, lung, and/or
Unusual Cancers of Childhood Treatment (PDQ®): Treatment - Patient Information [NCI]-Unusual Cancers of the Abdomen
Cancer of the Adrenal CortexThere are two adrenal glands. The adrenal glands are small and shaped like a triangle. One adrenal gland sits on top of each kidney. Each adrenal gland has two parts. The outer layer of the adrenal gland is the adrenal cortex. The center of the adrenal gland is the adrenal medulla. Cancer of the adrenal cortex is also called adrenocortical carcinoma. Childhood cancer of the adrenal cortex occurs most commonly in patients younger than 6 years or in the teen years, and more often in females.The adrenal cortex makes important hormones that do the following:Balance the water and salt in the body.Help keep blood pressure normal.Help control the body's use of protein, fat, and carbohydrates.Cause the body to have male or female characteristics.Risk Factors, Symptoms, and Diagnostic and Staging TestsThe risk of cancer of the adrenal cortex is increased by having any of the following syndromes:Li-Fraumeni syndrome.Beckwith-Wiedemann syndrome.Hemihypertrophy. A
Hunter Syndrome (MPS II)
Learn about Hunter syndrome, a rare genetic disease, and how it can be treated.
Are You Destined to Get Your Parents' Illnesses?
With conditions like cancer, Alzheimer's, diabetes, and heart disease, your genes aren't always destiny. You can likely overcome your heredity and stay disease-free by making smarter health decisions.
Crusade for a Cure
Battling a rare genetic disorder called pseudoxanthoma elasticum, or PXE.
Know Your Genetic Risk
Knowing your family's health history can help you avoid health problems yourself.
Battling Nature (Part 1): Genetic Possibilities
Learn more about the field of genetics and the future possibility of targeting certain genes to slow the aging process.
Slideshows & Images
X-Ray and MRI of Legg-Calve-Perthes Disease
Courtesy of Paul Traughber, M.D., Boise, Idaho.Figure 1 is an X - ray of a child's normal hipbone and a broken (fractured) hipbone from poor blood flow because of Legg - Calve - Perthes disease (LCPD). Figure 2 is an MRI of a child's normal hipbone with fat in the growth center and an abnormal hipbone where the fat has been lost because of LCPD. ...