Simpson Dysmorphia Syndrome
It is possible that the main title of the report Simpson Dysmorphia Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Bulldog Syndrome
- DGSX Golabi-Rosen Syndrome, Included
- Dysplasia Gigantism Syndrome, X-Linked
- SGB Syndrome
- Simpson-Golabi-Behmel Syndrome
- Simpson Dysmorphia Syndrome Type 1 (SDYS1)
- Simpson Dysmorphia Syndrome Type 2
Simpson dysmorphia syndrome types 1 and 2 are two forms of a rare, X-linked recessive, inherited disorder characterized by unusually large fetuses (prenatal overgrowth) and unusually large babies (postnatal overgrowth). In addition, affected individuals have characteristic facial features, more than two nipples (super-numerary nipples), and multisystemic malformations that may vary from child to child. Chief among these are cardiac malformations, mild to moderate mental retardation, cleft palate, and more than the five fingers and/or toes (polydactyly).
Symptoms associated with the more common form, Simpson dysmorphia syndrome type 1 (SDYS1), are less severe than those presented in SDYS2.
Individuals usually reach an above-average height. The general distinguishing features typically become less apparent in adulthood.
Children's Craniofacial Association
13140 Coit Road
Dallas, TX 75240
FACES: The National Craniofacial Association
PO Box 11082
Chattanooga, TN 37401
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
One AMS Circle
Bethesda, MD 20892-3675
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126